Phenol

Phenol

SCHEMBL11233732

CC1(C)Cc2ccccc2C1(C)C.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GLA P06280 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA14 Q9ULX7 1/20 0.41
HTR2A P28223 1/20 0.35
HSD17B10 Q99714 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
OPRD1 P41143 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2354334 0.88 HTR2A (0.42) HTR2A
SCHEMBL27964234 0.79 HSD17B10 (0.42) TDP1HSD17B10ESR1ESR2
SCHEMBL558875 0.76 HTR2A (0.39) HTR2A
SCHEMBL150397 0.73 SIGMAR1 (0.39) HTR2A
SCHEMBL29371697 0.73 SIGMAR1 (0.39) HTR2A
SCHEMBL9053415 0.73 HTR2A (0.41) HTR2A
SCHEMBL2046731 0.72 MAPK1 (0.40) HTR2A
Bicarbonate SCHEMBL8752098 0.71 HDAC9 (0.40)
SCHEMBL2388621 0.70 GABRA1 (0.39)
SCHEMBL19419858 0.70 CYP1A2 (0.40) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4316980-A USING A QUATERNARY AMMONIUM SALT CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1982-02-23 US disclosed