Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315505 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL11279590 | 0.83 | CES2 (0.66) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL10497166 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL67860 | 0.82 | ALDH1A1 (0.87) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL11377091 | 0.80 | CES2 (0.60) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL20943429 | 0.80 | ALDH1A1 (0.83) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL10830040 | 0.80 | MAPT (0.45) | ALDH1A1KDM4ETSHRRAB9ASMN1; SMN2 | |
| SCHEMBL7069661 | 0.78 | KDM4E (0.69) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL67861 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRHSD17B10RAB9A | |
| SCHEMBL11752785 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347248-A | DIURETICS | AMERICAN CYANAMID COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4344954-A | DIURETICS | AMERICAN CYANAMID COMPANY (US) | 1982-08-17 | — | — | US | disclosed |