Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969895 | 0.85 | HCAR2 (0.50) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL2969893 | 0.85 | HCAR2 (0.50) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL23666175 | 0.80 | HCAR2 (0.54) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL195983 | 0.80 | HCAR2 (0.54) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL195984 | 0.80 | HCAR2 (0.54) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL863510 | 0.80 | HCAR2 (0.54) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL5004970 | 0.79 | HCAR2 (0.44) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL5008509 | 0.79 | HCAR2 (0.44) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL5511234 | 0.79 | HCAR2 (0.44) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL17285584 | 0.79 | HCAR2 (0.52) | HCAR2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351954-A | INSECTICIDES, HERBICIDES, FUNGICIDE, ENZYME INHIBITORS | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1982-09-28 | — | — | US | disclosed |