Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11228751 | 0.98 | FOLH1 (0.45) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| Water SCHEMBL11229138 | 0.88 | FOLH1 (0.41) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL7110776 | 0.85 | FOLH1 (0.47) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL1114979 | 0.85 | FOLH1 (0.47) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL5555256 | 0.84 | KDM4E (0.51) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL11233838 | 0.83 | FOLH1 (0.46) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL7110802 | 0.83 | FOLH1 (0.46) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL1114895 | 0.83 | ALDH1A1 (0.49) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| Water SCHEMBL11228747 | 0.82 | FOLH1 (0.45) | FOLH1ALDH1A1LMNAKDM4EPOLB | |
| Water SCHEMBL11236810 | 0.82 | FOLH1 (0.37) | FOLH1ALDH1A1LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |