Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.83 |
| ▸ | SCN1A | P35498 | 1/20 | 0.69 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.69 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.64 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.64 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.64 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.64 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.64 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4983220 | 0.88 | ADRA2A (0.66) | ADRA2ASCN1ASCN2ASCN3AGRIN2D | |
| Phenacaine SCHEMBL24365 | 0.82 | SCN1A (1.00) | ADRA2ASCN1ASCN2ASCN3AALDH1A1 | |
| Phenacaine SCHEMBL16070026 | 0.82 | SCN1A (1.00) | ADRA2ASCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL9179995 | 0.81 | SIGMAR1 (0.66) | ADRA2ACRHBPCRHR2GRIN2DGRIN3B | |
| SCHEMBL17233866 | 0.81 | SIGMAR1 (0.66) | ADRA2ACRHBPCRHR2GRIN2DGRIN3B | |
| Phenacaine SCHEMBL24364 | 0.81 | SCN1A (0.97) | ADRA2ASCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL4984764 | 0.80 | ADRA2A (0.56) | ADRA2ASCN2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11328281 | 0.79 | ADRA2A (0.63) | ADRA2ASCN1ASCN2ASCN3AALDH1A1 | |
| Phenacaine SCHEMBL1652314 | 0.79 | SCN1A (0.94) | ADRA2ASCN1ASCN2ASCN3AALDH1A1 | |
| Phenacaine SCHEMBL30185782 | 0.79 | SCN1A (0.94) | ADRA2ASCN1ASCN2ASCN3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347310-A | INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-08-31 | — | — | US | disclosed |