Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234232 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTALDH1A1ICMTCYP1A2 | |
| SCHEMBL10277707 | 0.88 | ALDH1A1 (0.42) | SMN1; SMN2MAPTALDH1A1ICMT | |
| SCHEMBL7117245 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL7117253 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL4668975 | 0.81 | MAPT (0.57) | SMN1; SMN2MAPTALDH1A1ICMTKDM4E | |
| SCHEMBL4668974 | 0.81 | MAPT (0.57) | SMN1; SMN2MAPTALDH1A1ICMTKDM4E | |
| SCHEMBL11126772 | 0.80 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1ICMTKDM4E | |
| SCHEMBL2791101 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1CASP1TDP1 | |
| SCHEMBL8628765 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1CASP1TDP1 | |
| SCHEMBL2791099 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1CASP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57031656-A | — | — | None | — | — | JP | disclosed |
| JP-S5731656-A | S-ALKYL-N-ACETYL-CYSTEINAMIDE AND ITS PREPARATION | MITSUBISHI CHEM IND LTD | 1982-02-20 | — | — | JP | disclosed |
| JP-S05731656-A | — | — | 0001-01-01 | — | — | JP | disclosed |