Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791101 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL2791099 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL10975759 | 0.84 | CASP1 (0.44) | SMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL10976689 | 0.84 | CASP1 (0.44) | SMN1; SMN2ALDH1A1CASP1 | |
| SCHEMBL9759966 | 0.80 | MAPT (0.37) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL28968948 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPT | |
| SCHEMBL28968951 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPT | |
| SCHEMBL15722123 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPT | |
| SCHEMBL7117245 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL7117253 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTKDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728373-A | EXHIBITING DEEP SKIN PENETRATION | BEIERSDORF AG (DE) | 1998-03-17 | — | — | US | claimed |
| EP-0656774-B1 | COSMETIC AND DERMATOLOGICAL SUNSCREEN COMPOSITIONS CONTAINING THIOLS AND/OR THIOL DERIVATES | BEIERSDORF AG (DE) | 1997-01-22 | — | — | EP | claimed |
| EP-0035188-B1 | 2-PENEM COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHODS FOR THEIR PREPARATION | SCHERING CORPORATION (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4448782-A | BACTERICIDES | SCHERING CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4382949-A | 2-(Amino acid-thio)-1-carbapen-2-em-3-carboxylic acids and congeners | SCHERING CORPORATION (US) | 1983-05-10 | — | — | US | disclosed |
| EP-0035188-A1 | 2-Penem compounds, pharmaceutical compositions containing them and methods for their preparation | SCHERING CORPORATION (US) | 1981-09-09 | — | — | EP | disclosed |