Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Gluceptate Sodium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.95 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014727 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL147609 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL29725120 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluconic Acid SCHEMBL8607873 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL147610 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL2014725 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL1479586 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL11234262 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL11220711 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 | |
| Gluceptate Sodium SCHEMBL9319356 | 1.00 | LMNA (0.95) | LMNAPDE4ATDP1L3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354940-A | Sodium alumoglucoheptonate, a process for its preparation and its use as sequestering agent | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1982-10-19 | — | — | US | claimed |
| US-4297293-A | BY REACTION OF A SODIUM ALUMINATE WITH SODIUM GLUCOHEPTONATE | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV. N.SOL.O. (YU) | 1981-10-27 | — | — | US | claimed |
| EP-0014939-A2 | Sodium alumoglucoheptonate, a process for its preparation and its use as sequestering agent | LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (SI) | 1980-09-03 | — | — | EP | claimed |
| US-4354940-A | Sodium alumoglucoheptonate, a process for its preparation and its use as sequestering agent | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1982-10-19 | — | — | US | disclosed |
| US-4297293-A | BY REACTION OF A SODIUM ALUMINATE WITH SODIUM GLUCOHEPTONATE | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV. N.SOL.O. (YU) | 1981-10-27 | — | — | US | disclosed |
| EP-0014939-A2 | Sodium alumoglucoheptonate, a process for its preparation and its use as sequestering agent | LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (SI) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014939-A2 | Sodium alumoglucoheptonate, a process for its preparation and its use as sequestering agent | LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (SI) | 1980-09-03 | — | — | EP | disclosed |