SCHEMBL2014727

SCHEMBL2014727

O=C([O-])[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO.[Na+]

nearest known ligand 0.95

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A known ✓ P27815 1/20 0.64
CA4 known ✓ P22748 2/20 0.34
LMNA P02545 2/20 0.95
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.50
USP2 O75604 1/20 0.48
SLCO1B1 Q9Y6L6 1/20 0.48
KDM4E B2RXH2 2/20 0.37
OR51E2 Q9H255 1/20 0.33
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluceptate Sodium SCHEMBL147609 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL29725120 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluconic Acid SCHEMBL8607873 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL11234259 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL147610 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL2014725 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL1479586 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL11234262 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL11220711 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2
Gluceptate Sodium SCHEMBL9319356 1.00 LMNA (0.95) LMNAPDE4ATDP1L3MBTL1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9222010-B2 Pumpable geopolymers comprising a mixing aid and dispersing agent SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2015-12-29 US claimed
US-9222010-B2 Pumpable geopolymers comprising a mixing aid and dispersing agent SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2015-12-29 US disclosed
US-20120318175-A1 Pumpable Geopolymers Comprising A Mixing Aid and Dispersing Agent SCHLUMBERGER TECHNOLOGY CORPORATION 2012-12-20 US disclosed
EP-2338949-B1 Pumpable geopolymers comprising a mixing aid and dispersing agent SCHLUMBERGER SERVICES PETROL (FR) 2012-08-15 EP disclosed
EP-2338949-A1 Pumpable geopolymers comprising a mixing aid and dispersing agent Services Pétroliers Schlumberger (FR) 2011-06-29 EP disclosed
WO-2011072784-A1 PUMPABLE GEOPOLYMERS COMPRISING A MIXING AID AND DISPERSING AGENT SERVICES PETROLIERS SCHLUMBERGER (FR) 2011-06-23 WO disclosed