Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786550 | 0.84 | CSNK2A2 (0.55) | MAOBMAOAACHEKMT2AMEN1 | |
| SCHEMBL11234379 | 0.82 | ACHE (0.48) | MAOBMAOAACHESNCAKMT2A | |
| SCHEMBL11239562 | 0.81 | CA12 (0.57) | KMT2ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL11231789 | 0.80 | SNCA (0.51) | MAOBSNCAKMT2AMEN1POLB | |
| SCHEMBL11235228 | 0.77 | ACHE (0.41) | MAOBMAOAACHESNCAKMT2A | |
| SCHEMBL11223795 | 0.76 | PIM1 (0.51) | SNCAKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11236593 | 0.73 | MAOB (0.64) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL11482154 | 0.73 | ALDH1A1 (0.47) | KMT2AMEN1POLBSMN1; SMN2NPC1 | |
| SCHEMBL13030205 | 0.72 | ACHE (0.47) | ACHEKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL11227792 | 0.72 | CA12 (0.72) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309353-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4205082-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |