Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229722 | 0.80 | MAPT (0.36) | MAPTTP53KMT2AMEN1GAA | |
| SCHEMBL11231260 | 0.79 | MAPT (0.38) | MAPTTP53KMT2AMEN1GAA | |
| SCHEMBL7769273 | 0.79 | GAA (0.62) | KMT2AMEN1GAATDP1HTT | |
| SCHEMBL16838661 | 0.77 | HTT (0.44) | MAPTKMT2AMEN1GAATDP1 | |
| SCHEMBL253638 | 0.76 | MAPT (0.37) | MAPTTP53KMT2AMEN1GAA | |
| SCHEMBL11228122 | 0.74 | GAA (0.47) | MAPTTP53KMT2AMEN1GAA | |
| SCHEMBL3258004 | 0.73 | MAPT (0.50) | MAPTTP53KMT2AMEN1TDP1 | |
| SCHEMBL9426469 | 0.73 | TDP1 (0.64) | MAPTTP53KMT2AMEN1TDP1 | |
| SCHEMBL4563435 | 0.73 | TDP1 (0.47) | MAPTKMT2AMEN1GAATDP1 | |
| SCHEMBL9706307 | 0.73 | IDO1 (0.45) | MAPTTP53HTTCACNA1HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088595-A2 | Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |