SCHEMBL7769273

SCHEMBL7769273

C=CCc1nc2cc(Cl)c(Cl)cc2[nH]1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.62
HTT P42858 1/20 0.62
CACNA1G O43497 2/20 0.54
CACNA1H O95180 1/20 0.54
PRKAG1 P54619 4/20 0.53
PRKAA2 P54646 4/20 0.53
PRKAB1 Q9Y478 4/20 0.53
PRKAA1 Q13131 1/20 0.53
F10 P00742 1/20 0.49
PDE10A Q9Y233 1/20 0.46
AR P10275 4/20 0.46
RHEB Q15382 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
LMNA P02545 1/20 0.41
GRIK1 P39086 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228122 0.87 GAA (0.47) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL9486634 0.84 GAA (0.44) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL9486630 0.84 GAA (0.44) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL7028428 0.81 PRKAG1 (0.46) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL4563435 0.80 TDP1 (0.47) GAAHTTF10TDP1MEN1
SCHEMBL9426469 0.80 TDP1 (0.64) F10TDP1MEN1RAB9AKMT2A
SCHEMBL10596713 0.80 GAA (0.72) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL11231260 0.79 MAPT (0.38) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL11234733 0.79 MAPT (0.38) GAAHTTCACNA1GCACNA1HPRKAG1
SCHEMBL486213 0.78 GAA (0.70) GAAHTTCACNA1GCACNA1HPRKAG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1111451-A2 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2001-06-27 EP disclosed
EP-0915370-A1 Silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1999-05-12 EP disclosed
US-5126235-A Spectrally sensitized with cyanine or merocyanine dyes to match laser light wavelengths FUJI PHOTO FILM CO., LTD. (JP) 1992-06-30 US disclosed
EP-0088595-A2 Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed
EP-0047470-A1 Method for immunochemical measurement FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed