SCHEMBL9426469

SCHEMBL9426469

C=CCc1nc2ccc(Cl)cc2[nH]1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.64
ALDH1A1 P00352 3/20 0.55
HPGD P15428 3/20 0.55
MEN1 O00255 2/20 0.55
MAPT P10636 2/20 0.55
KMT2A Q03164 2/20 0.55
F10 P00742 1/20 0.55
RAB9A P51151 2/20 0.54
HTR3E A5X5Y0 1/20 0.51
HTR3B O95264 1/20 0.51
HTR3A P46098 1/20 0.51
BACE1 P56817 1/20 0.51
HTR3D Q70Z44 1/20 0.51
HTR3C Q8WXA8 1/20 0.51
KLK1 P06870 1/20 0.48
KLK5 Q9Y337 1/20 0.48
EGFR P00533 4/20 0.48
ERBB2 P04626 2/20 0.48
IDO1 P14902 1/20 0.48
PSMB8 P28062 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4563435 0.87 TDP1 (0.47) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL2407488 0.81 TDP1 (0.70) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL17513468 0.81 TDP1 (0.60) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL3258007 0.81 KMT2A (0.66) ALDH1A1HPGDMEN1MAPTKMT2A
SCHEMBL8595177 0.81 MAPT (0.44) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL7769273 0.80 GAA (0.62) TDP1MEN1KMT2AF10RAB9A
SCHEMBL30040705 0.80 TDP1 (0.72) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL656416 0.80 TDP1 (0.72) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL17513211 0.79 TDP1 (0.66) TDP1ALDH1A1HPGDMEN1MAPT
SCHEMBL8490941 0.78 TDP1 (0.70) TDP1ALDH1A1HPGDMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290675-A Nitrogen containing heterocycles such as oxazole, thiazole or selenazole groups as dyes FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US disclosed
US-5242790-A Photographic films with silver halide emulsions and cyanine dyes FUJI PHOTO FILM CO., LTD. (JP) 1993-09-07 US disclosed
US-5166042-A Multilayer color photographic member FUJI PHOTO FILM CO., LTD. (JP) 1992-11-24 US disclosed
US-5006449-A Black and white photographic for printing negatives of color film FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed
EP-0385496-A2 Color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-09-05 EP disclosed