SCHEMBL11234796

SCHEMBL11234796

O=S(=O)(Nc1ccc(Cl)c(Cl)c1)c1cccs1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 3/20 0.66
MEN1 O00255 6/20 0.65
KMT2A Q03164 6/20 0.65
MAPK1 P28482 2/20 0.65
LMNA P02545 2/20 0.65
HTT P42858 2/20 0.65
MAPT P10636 1/20 0.65
HPGD P15428 3/20 0.60
ALDH1A1 P00352 2/20 0.59
PKM P14618 3/20 0.59
TSHR P16473 1/20 0.58
HSD17B10 Q99714 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
TP53 P04637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888667 0.87 MEN1 (0.57) CCR2MEN1KMT2AMAPK1LMNA
SCHEMBL11698126 0.83 BRAF (0.65) CCR2MEN1KMT2AMAPK1LMNA
SCHEMBL29031229 0.83 MEN1 (0.77) MEN1KMT2ALMNAHTTMAPT
SCHEMBL8278381 0.82 HPGD (0.54) MEN1KMT2AMAPK1LMNAHTT
SCHEMBL13689982 0.81 HPGD (0.53) MEN1KMT2AMAPK1LMNAHTT
SCHEMBL9424746 0.80 MAPT (0.71) CCR2MEN1KMT2AMAPK1LMNA
SCHEMBL9930749 0.80 CCR2 (1.00) CCR2MEN1KMT2AMAPK1LMNA
SCHEMBL7570481 0.78 HPGD (0.68) MEN1KMT2AMAPK1LMNAHTT
SCHEMBL15479121 0.76 CCR2 (0.62) CCR2MEN1KMT2AMAPK1LMNA
SCHEMBL15479110 0.76 CCR2 (0.60) CCR2MEN1KMT2AMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349378-A Compounds useful as pesticides FBC LIMITED (GB) 1982-09-14 US disclosed
US-4309559-A PLANT GROWTH REGULATORS AND ESPECIALLY FUNGICIDES OR HERBICIDES FBC LIMITED (GB) 1982-01-05 US disclosed