Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179886 | 0.84 | HPGD (0.57) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30926989 | 0.84 | HPGD (0.57) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29031229 | 0.83 | MEN1 (0.77) | HPGDMEN1KMT2AHTTLMNA | |
| SCHEMBL7590525 | 0.82 | NPC1 (0.63) | HPGDKMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10192087 | 0.82 | HTT (0.88) | HPGDMEN1KMT2AHTTLMNA | |
| SCHEMBL259416 | 0.81 | HPGD (1.00) | HPGDMEN1KMT2AHTTLMNA | |
| SCHEMBL526530 | 0.78 | KDM4E (0.56) | HPGDMEN1KMT2AHTTLMNA | |
| SCHEMBL11234796 | 0.78 | CCR2 (0.66) | HPGDMEN1KMT2AHTTLMNA | |
| SCHEMBL4709087 | 0.76 | MEN1 (0.84) | HPGDMEN1KMT2AHTTLMNA | |
| SCHEMBL7578748 | 0.76 | MEN1 (0.67) | HPGDMEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |