Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29729671 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL30869258 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Water SCHEMBL8021034 | 0.98 | HTT (0.59) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL8083797 | 0.98 | DNM1 (0.57) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL6762129 | 0.98 | DNM1 (0.57) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Water SCHEMBL11790520 | 0.97 | DNM1 (0.55) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL10445238 | 0.87 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL7764453 | 0.85 | KMT2A (0.71) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL8720796 | 0.85 | KMT2A (0.71) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL7760973 | 0.85 | KMT2A (0.71) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181596-B1 | METHOD OF INHIBITING THE GROWTH OF MICROORGANISM IN AQUEOUS SYSTEMS USING A COMPOSITION COMPRISING LYSOZYME | BUCKMAN LABOR INC (US) | 2015-07-08 | — | — | EP | claimed |
| WO-2007100514-A1 | HALOPEROXIDASE TREATMENT TO CONTROL ALGAE | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070197388-A1 | Haloperoxidase treatment to control algae | BUCKMAN LABORATORIES INTERNATIONAL, INC. | 2007-08-23 | — | — | US | claimed |
| US-4311512-A | Bactericidal water-soluble complexes | POLYCRAFT LABORATORIES, INC., A CORP. OF NJ. | 1982-01-19 | — | — | US | claimed |
| US-3997705-A | Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |
| WO-2021252700-A1 | USE OF CHLORAMINES AND CATIONIC POLYMERS IN WATER TREATMENT | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| US-20210387876-A1 | USE OF CHLORAMINES AND CATIONIC POLYMERS IN WATER TREATMENT | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2021-12-16 | — | — | US | disclosed |
| US-11053641-B2 | Modified creping adhesive formulation and creping methods using same | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| EP-3768891-A1 | MODIFIED CREPING ADHESIVE FORMULATION AND CREPING METHODS USING SAME | Buckman Laboratories International, Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| US-20190292729-A1 | Modified Creping Adhesive Formulation And Creping Methods Using Same | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| EP-2181596-B1 | METHOD OF INHIBITING THE GROWTH OF MICROORGANISM IN AQUEOUS SYSTEMS USING A COMPOSITION COMPRISING LYSOZYME | BUCKMAN LABOR INC (US) | 2015-07-08 | — | — | EP | disclosed |
| US-8603453-B2 | Antimicrobial polymeric biguanide and acidic co-polymer composition and method of use | ARCH UK BIOCIDES LIMITED (GB) | 2013-12-10 | — | — | US | disclosed |
| US-5112871-A | ANTI-MICROBIAL BROMO-NITRO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0478173-A1 | Derivatives of 4,5-polymethylene-4-isothiazoline-3 ones and their use as biocides | ZENECA LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |
| WO-1992001380-A1 | BIOCIDE COMPOSITION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-06 | — | — | WO | disclosed |
| EP-0457435-A2 | Biocide composition and use | ZENECA LIMITED (GB) | 1991-11-21 | — | — | EP | disclosed |
| EP-0390394-A2 | Composition and use | ZENECA LIMITED (GB) | 1990-10-03 | — | — | EP | disclosed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| US-4311512-A | Bactericidal water-soluble complexes | POLYCRAFT LABORATORIES, INC., A CORP. OF NJ. | 1982-01-19 | — | — | US | disclosed |
| US-3997705-A | Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | disclosed |