Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242208 | 0.99 | HMOX1 (0.66) | HMOX1 | |
| Bromide SCHEMBL11246214 | 0.91 | HMOX1 (0.79) | HMOX1 | |
| SCHEMBL11236364 | 0.89 | HMOX1 (0.67) | HMOX1 | |
| SCHEMBL11243235 | 0.89 | HMOX1 (0.80) | HMOX1 | |
| Bromide SCHEMBL11239754 | 0.89 | HMOX1 (0.80) | HMOX1 | |
| SCHEMBL11241525 | 0.88 | HMOX1 (0.66) | HMOX1 | |
| SCHEMBL10249982 | 0.88 | HMOX1 (0.82) | HMOX1 | |
| SCHEMBL4431615 | 0.88 | HMOX1 (0.82) | HMOX1 | |
| SCHEMBL11242262 | 0.88 | HMOX1 (0.57) | HMOX1 | |
| SCHEMBL11249869 | 0.87 | HMOX1 (0.64) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |