Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10249982 | 0.99 | HMOX1 (0.82) | HMOX1 | |
| SCHEMBL4431615 | 0.99 | HMOX1 (0.82) | HMOX1 | |
| Hydrochloric Acid SCHEMBL410742 | 0.98 | HMOX1 (0.82) | HMOX1 | |
| SCHEMBL11244208 | 0.92 | HMOX1 (0.72) | HMOX1 | |
| Bromide SCHEMBL11241634 | 0.90 | HMOX1 (0.98) | HMOX1 | |
| Bromide SCHEMBL11234992 | 0.89 | HMOX1 (0.64) | HMOX1 | |
| SCHEMBL10246975 | 0.89 | HMOX1 (1.00) | HMOX1 | |
| SCHEMBL10247096 | 0.89 | HMOX1 (1.00) | HMOX1 | |
| SCHEMBL11245993 | 0.89 | HMOX1 (1.00) | HMOX1 | |
| SCHEMBL10247089 | 0.89 | HMOX1 (1.00) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |