Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL28533199 | 0.98 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Sebacic Acid SCHEMBL10578918 | 0.98 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Sebacic Acid SCHEMBL10578909 | 0.98 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Succinic Acid SCHEMBL9725171 | 0.91 | ALDH1A1 (0.59) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Hexanoate SCHEMBL2543601 | 0.91 | AKR1B1 (0.55) | ALDH1A1FKBP5TSHRSLC22A6TDP1 | |
| Hexanoate SCHEMBL29365616 | 0.89 | AKR1B1 (0.53) | ALDH1A1TSHRSLC22A6TDP1GPR84 | |
| Heptanoate SCHEMBL30184657 | 0.89 | PPARG (0.57) | ALDH1A1LMNATSHRSLC22A6TDP1 | |
| Dodecanoate SCHEMBL29512288 | 0.89 | PPARG (0.57) | ALDH1A1LMNATSHRSLC22A6TDP1 | |
| Dodecanoate SCHEMBL21647325 | 0.89 | PPARG (0.57) | ALDH1A1LMNATSHRSLC22A6TDP1 | |
| Imidazole SCHEMBL28421282 | 0.89 | ALDH1A1 (0.43) | ALDH1A1FKBP5LMNATBXAS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106757507-B | A kind of high-performance polyamide fibre base can contaminate conductive fiber and preparation method thereof | 北京中纺优丝特种纤维科技有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-106757507-A | A kind of high-performance polyamide fibre base can contaminate conductive fiber and preparation method thereof | 北京中纺优丝特种纤维科技有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-113563565-B | Thermo-sensitive solid amine curing agent and preparation method thereof | 郑州大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113563565-A | Thermo-sensitive solid amine curing agent and preparation method thereof | 郑州大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-106757507-B | A kind of high-performance polyamide fibre base can contaminate conductive fiber and preparation method thereof | 北京中纺优丝特种纤维科技有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-106757507-A | A kind of high-performance polyamide fibre base can contaminate conductive fiber and preparation method thereof | 北京中纺优丝特种纤维科技有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-102964568-B | Modified di-imidazole latent curing agent for epoxy resin and preparation method for same | UNIV EAST CHINA SCIENCE & TECH | 2014-08-27 | — | — | CN | disclosed |
| CN-102964568-A | Modified di-imidazole latent curing agent for epoxy resin and preparation method for same | UNIV EAST CHINA SCIENCE & TECH | 2013-03-13 | — | — | CN | disclosed |
| CN-102942682-A | Diimidazole alkane epoxy curing agent | UNIV EAST CHINA SCIENCE & TECH | 2013-02-27 | — | — | CN | disclosed |
| US-4312974-A | SALT OF PIPERAZINE AND POLYCARBOXYLIC ACID | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |
| US-4069203-A | ORGANIC DIBASIC ACID, IMIDAZOLE DERIVATIVE | SHELL OIL COMPANY (US) | 1978-01-17 | — | — | US | disclosed |