Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11235203 | 0.91 | ALDH1A1 (0.54) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Sebacic Acid SCHEMBL10578918 | 0.90 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Imidazole SCHEMBL5828948 | 0.90 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNAEGLN1ALKBH5 | |
| Imidazole SCHEMBL28533199 | 0.90 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Sebacic Acid SCHEMBL10578909 | 0.90 | ALDH1A1 (0.52) | ALDH1A1FKBP5LMNATBXAS1TSHR | |
| Butyric Acid SCHEMBL21632810 | 0.88 | ALDH1A1 (0.50) | ALDH1A1FKBP5EGLN3TSHROR51E2 | |
| Malonic Acid SCHEMBL14695335 | 0.86 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3TSHR | |
| Glycolic Acid SCHEMBL31731101 | 0.86 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3TSHR | |
| Malonic Acid SCHEMBL28601856 | 0.86 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3TSHR | |
| Butyric Acid SCHEMBL29364931 | 0.86 | ALDH1A1 (0.48) | ALDH1A1FKBP5EGLN3TSHROR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108245683-B | Anti-tumor prodrug with P-glycoprotein inhibition function and preparation method thereof | 华中科技大学 | 2020-02-14 | — | — | CN | claimed |
| CN-108245683-A | A kind of anti-tumor predrug and preparation method with the inhibition of P- glycoprotein | 华中科技大学 | 2018-07-06 | — | — | CN | claimed |
| CN-104625485-A | Water-soluble polymer hot-air leveling flux | SUZHOU LOTTE CHEMICAL TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-102584745-A | Method using glycerol and silicon tetrachloride to prepare epichlorohydrin and white carbon black | UNIV CHANGZHOU | 2012-07-18 | — | — | CN | claimed |
| CN-122059878-A | Bio-based latency accelerator and preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2026-05-19 | — | — | CN | disclosed |
| CN-119551719-A | Preparation method of anhydrous proton conductive electrolyte material based on supermolecule metal halide framework | 江苏中正陶瓷科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-108245683-B | Anti-tumor prodrug with P-glycoprotein inhibition function and preparation method thereof | 华中科技大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-108245683-A | A kind of anti-tumor predrug and preparation method with the inhibition of P- glycoprotein | 华中科技大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-106634709-B | A kind of oil filter hot setting adhesive and preparation method thereof | 佛山市豹王滤芯制造有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-106634709-A | Heat curing adhesive for oil filter and preparation method of heat curing adhesive | 佛山市豹王滤芯制造有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104625485-A | Water-soluble polymer hot-air leveling flux | SUZHOU LOTTE CHEMICAL TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-102584745-A | Method using glycerol and silicon tetrachloride to prepare epichlorohydrin and white carbon black | UNIV CHANGZHOU | 2012-07-18 | — | — | CN | disclosed |
| EP-0504732-A2 | Powder coating composition | Nippon Paint Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |