SCHEMBL11235249

SCHEMBL11235249

CCCCCCN1C2COCC1CC(NC(=O)c1cc(Cl)c(N)cc1OC)C2

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 10/20 0.68
DRD2 P14416 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236108 0.87 HTR4 (0.51) HTR4DRD2
SCHEMBL11243059 0.87 HTR4 (0.51) HTR4DRD2
SCHEMBL11235740 0.86 HTR4 (0.69) HTR4DRD2
SCHEMBL7292915 0.85 HTR4 (0.84) HTR4DRD2
SCHEMBL11237006 0.83 DRD2 (0.83) HTR4DRD2
SCHEMBL11228982 0.83 DRD2 (0.83) HTR4DRD2
SCHEMBL11237366 0.83 DRD2 (0.71) HTR4DRD2
SCHEMBL11237369 0.83 DRD2 (0.71) HTR4DRD2
SCHEMBL9022488 0.82 DRD2 (0.71) HTR4DRD2
SCHEMBL9021887 0.82 DRD2 (0.68) HTR4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4352802-A DESALINATION OF SEA WATER BEECHAM GROUP LIMITED (GB) 1982-10-05 US claimed
EP-0041817-A1 Benzamide derivatives, process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-12-16 EP claimed
US-4352802-A DESALINATION OF SEA WATER BEECHAM GROUP LIMITED (GB) 1982-10-05 US disclosed
EP-0041817-A1 Benzamide derivatives, process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-12-16 EP disclosed