Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603743 | 0.96 | ATM (0.44) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7603740 | 0.96 | ATM (0.44) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL5586794 | 0.84 | ATM (0.49) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL29401299 | 0.82 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL12203694 | 0.82 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL3676162 | 0.82 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL3676166 | 0.82 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL7622841 | 0.81 | ACACB (0.56) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL2742779 | 0.81 | ACACB (0.54) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL14588983 | 0.81 | ACACB (0.54) | ATMITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329281-A | AMPHETAMINE, METHAMPHETAMINE | HOFFMANN-LA ROCHE INC. (US) | 1982-05-11 | — | — | US | disclosed |