Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603743 | 1.00 | ATM (0.44) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL11235331 | 0.96 | ATM (0.45) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL5586794 | 0.83 | ATM (0.49) | ATMITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7610862 | 0.81 | ACACB (0.57) | MAPTRXFP1 | |
| SCHEMBL7610856 | 0.81 | ACACB (0.57) | MAPTRXFP1 | |
| SCHEMBL12203694 | 0.81 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL3676162 | 0.81 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL3676166 | 0.81 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL29401299 | 0.81 | NPC1 (0.63) | ATMCTSSCTSKACECTSL | |
| SCHEMBL7622841 | 0.80 | ACACB (0.56) | ATMITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820984-B1 | Activated amphetamines | ROCHE DIAGNOSTICS GMBH (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-5976812-A | Activated amphetamines | ROCHE DIAGNOSTICS GMBH (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0820984-A1 | Activated amphetamines | Roche Diagnostics GmbH (DE) | 1998-01-28 | — | — | EP | disclosed |