Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420391 | 0.84 | MAPK1 (0.48) | ALDH1A1MAPK1LMNASMN1; SMN2FAAH | |
| SCHEMBL6890292 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL10344105 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL2986945 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL2984393 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL11144445 | 0.81 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL11171620 | 0.79 | — | — | |
| SCHEMBL9964648 | 0.79 | TSHR (0.39) | ALDH1A1MAPK1HSD17B10TSHRMAPT | |
| SCHEMBL12310710 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL1717365 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | claimed |
| EP-0060904-A1 | A process for making vicinal epoxides and alkyl halides or alkylene dihalides from carbonate esters | THE DOW CHEMICAL COMPANY (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| US-4331604-A | Preparation of cyclic carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |
| US-4261906-A | DECOMPOSITION OF BETA-HALOALKYL CARBONATE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | THE DOW CHEMICAL COMPANY (US) | 1981-04-14 | — | — | US | disclosed |