SCHEMBL9964648

SCHEMBL9964648

CC(O)COC(=O)OC(C)CCl

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.38
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9964654 0.83 MAPT (0.40) TSHRALDH1A1MAPTMAPK1HSD17B10
SCHEMBL15503226 0.82 MAPK1 (0.34) TSHRMAPK1
SCHEMBL9964649 0.82 MAPT (0.43) TSHRALDH1A1MAPTMAPK1HSD17B10
SCHEMBL12262559 0.82 MAPT (0.39) TSHRMAPTMAPK1HSD17B10
SCHEMBL15441005 0.82 MAPT (0.39) TSHRMAPTMAPK1HSD17B10
SCHEMBL6420391 0.80 MAPK1 (0.48) TSHRALDH1A1MAPTMAPK1
SCHEMBL15383093 0.80 MAPT (0.38) TSHRMAPTMAPK1HSD17B10
SCHEMBL11235341 0.79 ALDH1A1 (0.50) TSHRALDH1A1MAPTMAPK1HSD17B10
SCHEMBL22953653 0.79 MAPT (0.42) TSHRALDH1A1MAPTMAPK1HSD17B10
SCHEMBL16233135 0.78 MAPT (0.37) TSHRMAPTMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9738784-B2 Polymer blends NOVOMER, INC. (US) 2017-08-22 US disclosed
US-8748555-B2 Structurally precise poly(propylene carbonate) compositions NOVOMER, INC. (US) 2014-06-10 US disclosed
US-20130209775-A1 POLYMER BLENDS NOVOMER, INC. (US) 2013-08-15 US disclosed
US-20120156410-A1 STRUCTURALLY PRECISE POLY(PROPYLENE CARBONATE) COMPOSITIONS NOVOMER, INC. (US) 2012-06-21 US disclosed