Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226260 | 0.87 | SMN1; SMN2 (0.47) | MAPTALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL11226153 | 0.84 | TSHR (0.35) | MAPTALDH1A1CYP1A2CYP2C19NPC1 | |
| SCHEMBL11690276 | 0.81 | SMN1; SMN2 (0.49) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11235712 | 0.80 | NPC1 (0.49) | MAPTALDH1A1NPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11235694 | 0.80 | NPC1 (0.49) | MAPTALDH1A1NPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11235406 | 0.79 | MAPT (0.44) | MAPTALDH1A1NPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11726763 | 0.78 | MEN1 (0.50) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11726774 | 0.78 | MEN1 (0.50) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9459291 | 0.75 | TDP1 (0.54) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6825169 | 0.74 | ALDH1A1 (0.59) | MAPTALDH1A1NPC1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |