Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PTPRG | P23470 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11690276 | 0.81 | SMN1; SMN2 (0.49) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL8345822 | 0.79 | TDP1 (0.62) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11842725 | 0.77 | TDP1 (0.61) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL22767269 | 0.76 | TDP1 (0.65) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL11235402 | 0.75 | MAPT (0.41) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL28398594 | 0.73 | MEN1 (0.46) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL14611678 | 0.73 | IDO1 (0.57) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL6689595 | 0.73 | IDO1 (0.68) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL10409192 | 0.73 | IDO1 (0.52) | TDP1L3MBTL1IDO1KMT2AMEN1 | |
| SCHEMBL22524929 | 0.72 | TDP1 (0.51) | TDP1L3MBTL1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189058-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1993-02-23 | — | — | US | claimed |