SCHEMBL1123541

SCHEMBL1123541

CCCCCCCC/C=C\CCCCCCCCN(CCCCCCCC/C=C\CCCCCCCC)CCC[Si](OC)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
FAAH O00519 3/20 0.40
TRPV1 Q8NER1 1/20 0.40
LPAR1 Q92633 1/20 0.39
LPAR2 Q9HBW0 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39
EPHX2 P34913 5/20 0.38
CNR1 P21554 1/20 0.36
TERT O14746 2/20 0.36
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
APEX1 P27695 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123545 1.00 LMNA (0.45) LMNAFAAHTRPV1LPAR1LPAR2
SCHEMBL31714786 0.89 LMNA (0.53) LMNA
SCHEMBL1116612 0.89 LMNA (0.53) LMNA
SCHEMBL8974867 0.89 LMNA (0.53) LMNA
SCHEMBL10882992 0.89 LMNA (0.53) LMNA
SCHEMBL1123594 0.89 LMNA (0.53) LMNA
SCHEMBL17800748 0.88 LMNA (0.50) LMNA
SCHEMBL2713411 0.86 LMNA (0.53) LMNAFAAHTRPV1LPAR1LPAR2
SCHEMBL5916766 0.86 LMNA (0.53) LMNA
Hydrochloric Acid SCHEMBL1685988 0.84 LMNA (0.52) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1997873-B1 Thickened surfactant-free cleasing and multifunctional liquid coating compositions containing nonreactive abrasive solid particles and an organosilane quaternary compound and methods of using RESOURCE DEV LLC (US) 2011-02-09 EP claimed