SCHEMBL1123594

SCHEMBL1123594

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCC[Si](OC)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
DNM1 Q05193 3/20 0.39
KDM5A P29375 2/20 0.34
PHF8 Q9UPP1 2/20 0.34
KDM4C Q9H3R0 1/20 0.34
KCNH2 Q12809 3/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ICMT O60725 1/20 0.32
ALB P02768 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1116612 1.00 LMNA (0.53) LMNADNM1KDM5APHF8KDM4C
SCHEMBL8974867 1.00 LMNA (0.53) LMNADNM1KDM5APHF8KDM4C
SCHEMBL10882992 1.00 LMNA (0.53) LMNADNM1KDM5APHF8KDM4C
SCHEMBL31714786 1.00 LMNA (0.53) LMNADNM1KDM5APHF8KDM4C
SCHEMBL17800748 0.98 LMNA (0.50) LMNADNM1KDM5APHF8KDM4C
SCHEMBL5916766 0.96 LMNA (0.53) LMNADNM1KDM5APHF8KDM4C
Hydrochloric Acid SCHEMBL1685988 0.94 LMNA (0.52) LMNADNM1KDM5APHF8KDM4C
SCHEMBL1567057 0.91 LMNA (0.47) LMNAKDM5AKCNH2CA12CA1
SCHEMBL992683 0.91 LMNA (0.47) LMNAKDM5AKCNH2CA12CA1
SCHEMBL9791643 0.91 LMNA (0.46) LMNADNM1KDM5APHF8KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1997873-B1 Thickened surfactant-free cleasing and multifunctional liquid coating compositions containing nonreactive abrasive solid particles and an organosilane quaternary compound and methods of using RESOURCE DEV LLC (US) 2011-02-09 EP claimed