Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24211953 | 0.84 | ALDH1A1 (0.53) | CYP1A2CYP3A4CYP2D6TSHRKDM4E | |
| SCHEMBL18468590 | 0.82 | L3MBTL1 (0.54) | CYP1A2CYP3A4KDM4EMAPTHPGD | |
| SCHEMBL29385431 | 0.82 | L3MBTL1 (0.54) | CYP1A2CYP3A4KDM4EMAPTHPGD | |
| SCHEMBL4201340 | 0.82 | L3MBTL1 (0.54) | CYP1A2CYP3A4KDM4EMAPTHPGD | |
| SCHEMBL16332656 | 0.82 | L3MBTL1 (0.54) | CYP1A2CYP3A4KDM4EMAPTHPGD | |
| SCHEMBL18468613 | 0.82 | L3MBTL1 (0.54) | CYP1A2CYP3A4KDM4EMAPTHPGD | |
| SCHEMBL10601440 | 0.82 | ALDH1A1 (0.58) | CYP1A2CYP3A4CYP2D6TSHRKDM4E | |
| SCHEMBL28243450 | 0.82 | L3MBTL1 (0.58) | TSHRKDM4EMAPTHPGDLMNA | |
| SCHEMBL106948 | 0.82 | L3MBTL1 (0.58) | TSHRKDM4EMAPTHPGDLMNA | |
| SCHEMBL19295118 | 0.80 | MEN1 (0.47) | CYP1A2CYP3A4CYP2D6TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051067-A1 | TRIAZINE SYNTHESIS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-05-12 | — | — | EP | disclosed |
| WO-1981003020-A1 | TRIAZINE SYNTHESIS | COMMW SCIENT IND RES ORG (AU) | 1981-10-29 | — | — | WO | disclosed |