Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241064 | 0.83 | MEN1 (0.43) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11475408 | 0.81 | TBXAS1 (0.39) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11236134 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11250408 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11480630 | 0.80 | MAPK1 (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11480623 | 0.80 | MAPK1 (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10918279 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2ATDP1ALDH1A1MAPK1 | |
| SCHEMBL11488879 | 0.78 | TP53 (0.37) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11488880 | 0.78 | TP53 (0.37) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11249308 | 0.77 | POLB (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |