Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243674 | 0.93 | MAOB (0.33) | MAOBMAOAL3MBTL1GSK3BLMNA | |
| SCHEMBL11239184 | 0.85 | CHRNA1 (0.35) | MAOBMAOAL3MBTL1CHRNA1CHRNG | |
| SCHEMBL11239172 | 0.83 | MAOA (0.34) | MAOBMAOAGSK3BLMNASLC6A3 | |
| SCHEMBL4613107 | 0.83 | L3MBTL1 (0.33) | MAOBMAOAL3MBTL1LMNACHRNA1 | |
| SCHEMBL4783521 | 0.82 | L3MBTL1 (0.43) | MAOBMAOAL3MBTL1 | |
| SCHEMBL11250705 | 0.82 | MAOB (0.39) | MAOBMAOAGSK3BCHRNA1CHRNG | |
| SCHEMBL11238206 | 0.82 | POLB (0.34) | — | |
| SCHEMBL3891785 | 0.82 | MAOB (0.38) | MAOBMAOAL3MBTL1GSK3BLMNA | |
| SCHEMBL2084122 | 0.81 | CNR1 (0.40) | L3MBTL1 | |
| SCHEMBL11241311 | 0.81 | L3MBTL1 (0.32) | MAOBMAOAL3MBTL1LMNACHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |