Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686334 | 0.91 | CYP1A2 (0.55) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| SCHEMBL10681118 | 0.86 | MAPT (0.52) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| Quizalofop SCHEMBL63325 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| R(+)Xk469 SCHEMBL1958606 | 0.82 | ALDH1A1 (0.80) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| SCHEMBL10736012 | 0.82 | CYP1A2 (0.52) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| Quizalofop SCHEMBL1010164 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| Quizalofop SCHEMBL111413 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| R(+)Xk469 SCHEMBL10261981 | 0.82 | ALDH1A1 (0.80) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| Quizalofop SCHEMBL19210826 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP1A2MAPTTP53 | |
| R(+)Xk469 SCHEMBL31494114 | 0.82 | ALDH1A1 (0.80) | ALDH1A1HPGDCYP1A2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063866-A1 | Quinolin-3-yloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them, and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-11-03 | — | — | EP | disclosed |