Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | GMNN | O75496 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quizalofop SCHEMBL29763487 | 1.00 | ALDH1A1 (0.72) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| Quizalofop SCHEMBL111413 | 1.00 | ALDH1A1 (0.72) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| Quizalofop SCHEMBL19210826 | 1.00 | ALDH1A1 (0.72) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| Quizalofop SCHEMBL63325 | 1.00 | ALDH1A1 (0.72) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| Quizalofop SCHEMBL10942454 | 0.99 | ALDH1A1 (0.71) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| Quizalofop SCHEMBL10847222 | 0.97 | CYP1A2 (0.69) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| R(+)Xk469 SCHEMBL10261981 | 0.95 | ALDH1A1 (0.80) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| R(+)Xk469 SCHEMBL1958606 | 0.95 | ALDH1A1 (0.80) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| R(+)Xk469 SCHEMBL30064428 | 0.95 | ALDH1A1 (0.80) | ALDH1A1CYP1A2MAPTHPGDNPSR1 | |
| R(+)Xk469 SCHEMBL31494114 | 0.95 | ALDH1A1 (0.80) | ALDH1A1CYP1A2MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2022-03-29 | — | — | US | claimed |
| US-20210000843-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2021-01-07 | — | — | US | claimed |
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY (US) | 2020-05-12 | — | — | US | claimed |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2019-08-29 | — | — | US | claimed |
| US-10292992-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2019-05-21 | — | — | US | claimed |
| US-9884070-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-02-06 | — | — | US | claimed |
| US-20180008621-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-01-11 | — | — | US | claimed |
| US-20180008622-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-01-11 | — | — | US | claimed |
| EP-2268654-B1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | UNIV CALIFORNIA (US) | 2017-01-25 | — | — | EP | claimed |
| US-20110144065-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | U.S. DEPARTMENT OF ENERGY | 2011-06-16 | — | — | US | claimed |
| EP-2268654-A2 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | The Regents of the University of California (US) | 2011-01-05 | — | — | EP | claimed |
| WO-2009132020-A2 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-29 | — | — | WO | claimed |
| US-20080114168-A1 | Novel esters as useful broad spectrum herbicidal compounds | CORET JOEL M | 2008-05-15 | — | — | US | claimed |
| WO-2006009964-A2 | NOVEL ESTERS AS USEFUL HERBICIDAL COMPOUNDS | CORET JOEL MARCEL (US) | 2006-01-26 | — | — | WO | claimed |
| US-20050282708-A1 | Novel esters as useful herbicidal compounds | CORET JOEL M | 2005-12-22 | — | — | US | claimed |
| US-5409885-A | Plant safening agent and nonionic surfactant | RHONE-POULENC CHIMIE (FR) | 1995-04-25 | — | — | US | claimed |
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2022-03-29 | — | — | US | disclosed |
| EP-3897137-A1 | HERBICIDAL COMBINATIONS | BASF Agrochemical Products B.V. (NL) | 2021-10-27 | — | — | EP | disclosed |
| EP-0648413-A1 | Alkylsiloxanes as adjuvants for agriculture | OSi Specialties, Inc. (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0351021-A2 | Herbicide mixtures | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-20050282708-A1 | Novel esters as useful herbicidal compounds | NOTUM, DDT, HDHD5 | ALDH1A1 180/4885CYP1A2 754/4885MAPT 4328/4885 |
| US-20110144065-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-20180008621-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-20180008622-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-20080114168-A1 | Novel esters as useful broad spectrum herbicidal compounds | NOTUM, DDT, HDHD5 | ALDH1A1 164/4885CYP1A2 540/4885MAPT 4328/4885 |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-20210000843-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
| US-10292992-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | ALDH1A1 3536/4885CYP1A2 4822/4885MAPT 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.