Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227278 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL11240393 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL10576685 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL11235403 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL11242222 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL11234116 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| Hydrochloric Acid SCHEMBL11237558 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL5458094 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 | |
| SCHEMBL11305021 | 0.92 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10FFAR1 | |
| SCHEMBL6031792 | 0.92 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10PLA2G4BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |