Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235403 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11242222 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11235833 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11234116 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11240393 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11227278 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL10576685 | 0.93 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| Hydrochloric Acid SCHEMBL11237558 | 0.92 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11038206 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10FFAR1RAB9A | |
| SCHEMBL11306401 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759674-B | Catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-20070010526-A1 | Therapeutic isoquinoline compounds | ASTRAZENECA AB (SE) | 2007-01-11 | — | — | US | disclosed |
| EP-1451172-A1 | THERAPEUTIC ISOQUINOLINE COMPOUNDS | AstraZeneca AB (SE) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003037887-A1 | THERAPEUTIC ISOQUINOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-05-08 | — | — | WO | disclosed |
| EP-0701997-B1 | Reaction products of anilines and bisphenolgylcidylethers, a process for their preparation and their use as hardening accelerators | BAYER AG (DE) | 2000-02-16 | — | — | EP | disclosed |
| EP-0701997-A1 | Reaction products of anilines and bisphenolgylcidylethers, a process for their preparation and their use as hardening accelerators | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0052296-B1 | GLUTAMINE DERIVATIVES USABLE FOR CURING IMMUNE DISEASES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS COMPRISING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1984-06-27 | — | — | EP | disclosed |
| US-4439554-A | DENTISTRY, ORTHOPEDICS | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1984-03-27 | — | — | US | disclosed |
| US-4439448-A | IMMUNOMODULATING ACTIVITY | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1984-03-27 | — | — | US | disclosed |
| US-4390714-A | DENTISTRY | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0052296-A1 | Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-26 | — | — | EP | disclosed |
| US-4243763-A | DENTISTRY | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-3957850-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | BOUCHARA EMILE | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010526-A1 | Therapeutic isoquinoline compounds | HTR1B, HTR1D, HTR1A | ALDH1A1 816/4885HPGD 918/4885HSD17B10 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.