SCHEMBL11235834

SCHEMBL11235834

CC1CC(C)(C)Cc2nc(N3C(=O)N(C)CC3O)sc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11111699 0.79 ALDH1A1 (0.53) NPC1ALDH1A1RAB9A
SCHEMBL11230041 0.78 NPC1 (0.31) NPC1ALDH1A1RAB9A
SCHEMBL11237920 0.70 TSHR (0.36) NPC1ALDH1A1RAB9A
SCHEMBL10734767 0.70 PIK3CD (0.52)
SCHEMBL10367815 0.67 ALDH1A1 (0.54) NPC1ALDH1A1RAB9A
SCHEMBL11633084 0.67 LMNA (0.48) NPC1ALDH1A1RAB9A
SCHEMBL10743729 0.67 ALDH1A1 (0.50) NPC1ALDH1A1RAB9A
SCHEMBL11227526 0.65 ALDH1A1 (0.47) ALDH1A1
SCHEMBL11555280 0.65 RXFP1 (0.33) ALDH1A1
SCHEMBL11751039 0.64 CA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4319914-A POSTEMERGENCE HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1982-03-16 US disclosed