Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258333 | 0.93 | STAT3 (0.62) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10518799 | 0.92 | STAT3 (0.53) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL11229199 | 0.91 | KMT2A (0.56) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10619432 | 0.88 | KMT2A (0.53) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10330760 | 0.85 | KDM4E (0.68) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31151754 | 0.85 | STAT3 (0.54) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16026588 | 0.85 | STAT3 (0.54) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10517272 | 0.85 | STAT3 (0.53) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL11193162 | 0.85 | STAT3 (0.61) | STAT3KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9636784 | 0.84 | KDM4E (0.76) | STAT3KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028698-B1 | QUINOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1982-12-22 | — | — | EP | disclosed |
| US-4327101-A | Quinoline compound useful as antibacterial agents in warm-blooded animals | TANABE SEIKAKU CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0028698-A1 | Quinoline compounds, process for their preparation, and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1981-05-20 | — | — | EP | disclosed |