Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | STAT3 | P40763 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895231 | 0.93 | STAT3 (0.61) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL6756451 | 0.93 | STAT3 (0.61) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL9442764 | 0.92 | LMNA (0.58) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL11235862 | 0.91 | STAT3 (0.54) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL15999503 | 0.90 | TDP1 (0.55) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL10459763 | 0.90 | STAT3 (0.56) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL9186530 | 0.88 | LMNA (0.57) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL10623495 | 0.87 | KMT2A (0.55) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL584246 | 0.87 | STAT3 (0.58) | KMT2ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL9442738 | 0.86 | KMT2A (0.60) | KMT2ATDP1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028698-B1 | QUINOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1982-12-22 | — | — | EP | disclosed |
| US-4327101-A | Quinoline compound useful as antibacterial agents in warm-blooded animals | TANABE SEIKAKU CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0028698-A1 | Quinoline compounds, process for their preparation, and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1981-05-20 | — | — | EP | disclosed |