Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635375 | 0.90 | KDM4E (0.62) | KDM4EKMT2AMEN1ALDH1A1STAT3 | |
| SCHEMBL13576353 | 0.90 | KDM4E (0.79) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9636861 | 0.89 | KDM4E (0.71) | KDM4EKMT2AMEN1ALDH1A1STAT3 | |
| SCHEMBL9633508 | 0.86 | KDM4E (0.58) | KDM4EKMT2AMEN1ALDH1A1STAT3 | |
| Fleroxacin SCHEMBL48145 | 0.86 | KDM4E (1.00) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL29377022 | 0.86 | KDM4E (1.00) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5258333 | 0.86 | STAT3 (0.62) | KDM4EKMT2AALDH1A1STAT3HPGD | |
| Fleroxacin SCHEMBL9745337 | 0.85 | KDM4E (0.98) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL11193870 | 0.85 | KDM4E (0.98) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL9745354 | 0.85 | KDM4E (0.98) | KDM4EKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195135-B1 | A PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACID DERIVATIVES | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1992-06-17 | — | — | EP | disclosed |
| EP-0195135-A1 | A process for the preparation of quinoline carboxylic acid derivatives | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1986-09-24 | — | — | EP | disclosed |