SCHEMBL1567057

SCHEMBL1567057

CCCCN(CCC[Si](OC)(OC)OC)CCC[Si](OC)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
ATP4A P20648 3/20 0.33
ATP4B P51164 3/20 0.33
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
HTR1B P28222 1/20 0.31
KDM5A P29375 1/20 0.31
MAPT P10636 1/20 0.31
CYP1A2 P05177 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
HTR1A P08908 1/20 0.30
GAA P10253 1/20 0.30
CYP2D6 P10635 1/20 0.30
DRD3 P35462 1/20 0.30
SCN1A P35498 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992683 1.00 LMNA (0.47) LMNAATP4AATP4BHSP90AA1HSP90AB1
SCHEMBL17800748 0.93 LMNA (0.50) LMNAKDM5AKCNH2
SCHEMBL7938343 0.93 LMNA (0.46) LMNAATP4AATP4BHSP90AA1HSP90AB1
SCHEMBL8974867 0.91 LMNA (0.53) LMNACA12CA1CA9KDM5A
SCHEMBL1123594 0.91 LMNA (0.53) LMNACA12CA1CA9KDM5A
SCHEMBL31714786 0.91 LMNA (0.53) LMNACA12CA1CA9KDM5A
SCHEMBL1116612 0.91 LMNA (0.53) LMNACA12CA1CA9KDM5A
SCHEMBL10882992 0.91 LMNA (0.53) LMNACA12CA1CA9KDM5A
SCHEMBL1116592 0.91 LMNA (0.42) LMNA
SCHEMBL8975121 0.91 LMNA (0.42) LMNAATP4AATP4BHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873415-B2 Substrate with water repellent oil repellent layer, vapor deposition material, and method for producing substrate with water repellent oil repellent layer AGC Inc. (JP) 2024-01-16 US disclosed
US-20230220236-A1 COMPOSITION, SUBSTRATE WITH SURFACE LAYER, METHOD FOR PRODUCING SUBSTRATE WITH SURFACE LAYER, COMPOUNDS, AND METHODS FOR PRODUCING COMPOUNDS AGC Inc. (JP) 2023-07-13 US disclosed
US-11643571-B2 Composition for forming water repellent film, water repellent film, substrate with water repellent film, and article AGC Inc. (JP) 2023-05-09 US disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-20180142062-A1 FLUORINATED ETHER COMPOUND, FLUORINATED ETHER COMPOSITION, COATING LIQUID AND ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2018-05-24 US disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-9416252-B2 Rubber composition for tire tread THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-08-16 US disclosed
US-9139721-B2 Rubber composition for tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-09-22 US disclosed
US-20130338255-A1 RUBBER COMPOSITION FOR TIRE TREAD THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-12-19 US disclosed
US-20130324638-A1 RUBBER COMPOSITION FOR USE IN TIRE TREADS THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-12-05 US disclosed
US-20130267646-A1 RUBBER COMPOSITION FOR TIRE TREAD AND PNEUMATIC TIRE USING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-10-10 US disclosed
EP-2307428-B1 PROCESS FOR PREPARING ALKYLAMINOALKYLALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2013-07-10 EP disclosed
US-8426628-B2 Process for preparing alkylaminoalkylalkoxysilanes EVONIK DEGUSSA GMBH (DE) 2013-04-23 US disclosed
EP-2003146-B1 USE OF A CONJUGATED DIENE RUBBER FOR A TIRE ZEON CORP (JP) 2012-12-26 EP disclosed
EP-2307428-A1 PROCESS FOR PREPARING ALKYLAMINOALKYLALKOXYSILANES Evonik Degussa GmbH (DE) 2011-04-13 EP disclosed
WO-2009146971-A1 PROCESS FOR PREPARING ALKYLAMINOALKYLALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2009-12-10 WO disclosed
EP-2003146-A9 CONJUGATED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION FOR TIRE, AND TIRE ZEON CORPORATION (JP) 2009-05-06 EP disclosed
EP-2003146-A2 CONJUGATED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION FOR TIRE, AND TIRE ZEON CORPORATION (JP) 2008-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220236-A1 COMPOSITION, SUBSTRATE WITH SURFACE LAYER, METHOD FOR PRODUCING SUBSTRATE WITH SURFACE LAYER, COMPOUNDS, AND METHODS FOR PRODUCING COMPOUNDS ZRANB2, ITGB1, ITGB2 LMNA 219/4885ATP4A 3955/4885ATP4B 2923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.