Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | CPA1 | P15085 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123211 | 1.00 | GPR132 (0.64) | GPR132PTPN1PPARGMMEACE | |
| SCHEMBL1123256 | 1.00 | GPR132 (0.64) | GPR132PTPN1PPARGMMEACE | |
| SCHEMBL1123184 | 0.94 | GPR132 (0.67) | GPR132PTPN1PPARGMMEACE | |
| SCHEMBL1123685 | 0.92 | RAB9A (0.71) | GPR132PTPN1PPARGRAB9AGAA | |
| SCHEMBL1122923 | 0.92 | RAB9A (0.71) | GPR132PTPN1PPARGRAB9AGAA | |
| SCHEMBL1123687 | 0.92 | RAB9A (0.71) | GPR132PTPN1PPARGRAB9AGAA | |
| SCHEMBL27638041 | 0.92 | RAB9A (0.71) | GPR132PTPN1PPARGRAB9AGAA | |
| SCHEMBL1122857 | 0.91 | GPR132 (0.67) | GPR132PTPN1PPARGMMEACE | |
| SCHEMBL27659028 | 0.91 | GPR132 (0.67) | GPR132PTPN1PPARGMMEACE | |
| SCHEMBL27638098 | 0.91 | GPR132 (0.77) | GPR132PTPN1GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |