SCHEMBL11236129

SCHEMBL11236129

CCCCCCCCCCCCCCCCCCCCOS(C)(=O)=O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.75
KDM4E B2RXH2 1/20 0.75
USP2 O75604 1/20 0.75
ALDH1A1 P00352 1/20 0.75
LMNA P02545 1/20 0.75
MMP9 P14780 1/20 0.75
ALOX15 P16050 1/20 0.75
CA1 P00915 15/20 0.64
CA2 P00918 15/20 0.64
CA9 Q16790 13/20 0.64
CA12 O43570 4/20 0.64
CA7 P43166 4/20 0.64
CA14 Q9ULX7 4/20 0.64
CA3 P07451 3/20 0.64
CA4 P22748 3/20 0.64
CA6 P23280 3/20 0.64
CA5A P35218 3/20 0.64
CA5B Q9Y2D0 3/20 0.64
RECQL P46063 2/20 0.61
GLA P06280 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11748392 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL5605250 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
Methanesulfonic Acid Dodecyl Ester SCHEMBL2223590 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL7726676 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL1899016 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL11225069 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL1443722 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL908020 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL3092383 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL140845 1.00 TSHR (0.75) TSHRKDM4EUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9958576-B2 Near infrared ray absorbent composition, near infrared ray cut filter, manufacturing method of near infrared ray cut filter, solid image pickup element, camera module FUJIFILM CORPORATION (JP) 2018-05-01 US disclosed
US-9707292-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2017-07-18 US disclosed
US-9657182-B2 Curable resin composition, production method of image sensor chip using the same, and image sensor chip FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9657182-B2 Curable resin composition, production method of image sensor chip using the same, and image sensor chip FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-20170102483-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, MANUFACTURING METHOD OF NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-04-13 US disclosed
US-20160199485-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2016-07-14 US disclosed
US-20160091643-A1 CURABLE COMPOSITION, CURED FILM, NEAR INFRARED CUT FILTER, CAMERA MODULE AND METHOD FOR MANUFACTURING CAMERA MODULE FUJIFILM CORPORATION (JP) 2016-03-31 US disclosed
US-20160091643-A1 CURABLE COMPOSITION, CURED FILM, NEAR INFRARED CUT FILTER, CAMERA MODULE AND METHOD FOR MANUFACTURING CAMERA MODULE FUJIFILM CORPORATION (JP) 2016-03-31 US disclosed
US-9186325-B2 Lipids and compositions for the delivery of therapeutics TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2015-11-17 US disclosed
US-20150259547-A1 CURABLE RESIN COMPOSITION, PRODUCTION METHOD OF IMAGE SENSOR CHIP USING THE SAME, AND IMAGE SENSOR CHIP FUJIFILM CORPORATION (JP) 2015-09-17 US disclosed
US-20150259547-A1 CURABLE RESIN COMPOSITION, PRODUCTION METHOD OF IMAGE SENSOR CHIP USING THE SAME, AND IMAGE SENSOR CHIP FUJIFILM CORPORATION (JP) 2015-09-17 US disclosed
US-20130079383-A1 Lipid Compounds Targeting VLA-4 ARROWHEAD RESEARCH CORPORATION (US) 2013-03-28 US disclosed
US-20110311582-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2011-12-22 US disclosed
US-4310471-A SURFACTANTS EXXON RESEARCH & ENGINEERING CO. (US) 1982-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160199485-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS PHOSPHO1, MBOAT1, SGMS1 TSHR 892/4885KDM4E 2104/4885USP2 2849/4885
US-20110311582-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS APOB, LPAR3, LPAR2 TSHR 1104/4885KDM4E 1001/4885USP2 2744/4885
US-20130079383-A1 Lipid Compounds Targeting VLA-4 LPAR4, ASGR1, VCAM1 TSHR 1081/4885KDM4E 1613/4885USP2 4837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.