Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.69 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237808 | 0.86 | MAOB (0.62) | MAOBHSD17B3CA12CA1CA9 | |
| SCHEMBL11232986 | 0.83 | MAOB (0.49) | MAOBCA12CA1CA9KDM4E | |
| SCHEMBL11236593 | 0.81 | MAOB (0.64) | MAOBHSD17B3CA12CA1CA9 | |
| SCHEMBL11232995 | 0.81 | CA12 (0.74) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL10880139 | 0.78 | MAOB (0.60) | MAOBHSD17B3KDM4EALDH1A1HPGD | |
| SCHEMBL11231762 | 0.78 | ALDH1A1 (0.63) | MAOBCA12CA1CA9KDM4E | |
| SCHEMBL9074252 | 0.75 | MAOB (0.50) | MAOBALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL11231792 | 0.74 | SNCA (0.45) | MAOBCA12CA1CA9ALDH1A1 | |
| SCHEMBL5191043 | 0.74 | MAOB (0.68) | MAOBHSD17B3CA12CA9KDM4E | |
| SCHEMBL11234379 | 0.72 | ACHE (0.48) | MAOBCA12CA9KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309353-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4205082-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |