Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392599 | 0.95 | NPC1 (0.49) | NPC1RAB9ALMNAHPGDKIT | |
| SCHEMBL11230533 | 0.91 | TYK2 (0.53) | NPC1RAB9ALMNAHPGDKIT | |
| SCHEMBL11382243 | 0.91 | ALDH1A1 (0.58) | NPC1RAB9ALMNAKITPDGFRA | |
| SCHEMBL11244512 | 0.88 | NPC1 (0.50) | NPC1RAB9ALMNAHPGDKIT | |
| SCHEMBL11240579 | 0.87 | NPC1 (0.49) | NPC1RAB9ALMNAHPGDKIT | |
| SCHEMBL11241049 | 0.87 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL396610 | 0.87 | TDP1 (0.61) | NPC1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11254337 | 0.85 | RORC (0.52) | NPC1RAB9AHPGDKITPDGFRA | |
| SCHEMBL11241366 | 0.85 | FFAR1 (0.53) | NPC1RAB9ALMNAHPGDKIT | |
| SCHEMBL11245388 | 0.84 | TP53 (0.49) | NPC1RAB9ALMNAHPGDKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |