Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236808 | 1.00 | LMNA (0.53) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| Bromide SCHEMBL11770679 | 0.98 | LMNA (0.51) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| Bromide SCHEMBL11781114 | 0.98 | LMNA (0.51) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL11230219 | 0.92 | ALDH1A1 (0.61) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL11230215 | 0.92 | ALDH1A1 (0.61) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11771736 | 0.91 | KDM4E (0.59) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11771741 | 0.91 | KDM4E (0.59) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL13673595 | 0.88 | ALDH1A1 (0.56) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL13673596 | 0.88 | ALDH1A1 (0.56) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL13380939 | 0.87 | MEN1 (0.57) | LMNAALDH1A1GAASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310541-A | WITH A BIS(BENZYLIDENEAMINO)GUANIDINE | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | claimed |
| US-4310541-A | WITH A BIS(BENZYLIDENEAMINO)GUANIDINE | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | disclosed |