Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.49 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.48 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123678 | 1.00 | GPR132 (0.60) | GPR132PTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL1122748 | 0.92 | GAA (0.59) | GPR132PTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL1123610 | 0.86 | GPR132 (0.64) | GPR132PTPN1ITGB3ITGA2BPPARG | |
| SCHEMBL1123333 | 0.85 | GPR132 (0.67) | GPR132PTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL1123112 | 0.85 | PTPN1 (0.64) | GPR132PTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL1123264 | 0.84 | GPR132 (0.68) | GPR132PTPN1ITGB3ITGA2BITGB1 | |
| SCHEMBL1123299 | 0.84 | GPR132 (0.77) | GPR132PTPN1ITGB3ITGA2BPPARG | |
| SCHEMBL1123033 | 0.84 | GPR132 (0.77) | GPR132PTPN1ITGB3ITGA2BPPARG | |
| SCHEMBL1123232 | 0.84 | GPR132 (0.77) | GPR132PTPN1ITGB3ITGA2BPPARG | |
| SCHEMBL27658914 | 0.84 | GPR132 (0.77) | GPR132PTPN1ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |