Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.75 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.75 |
| ▸ | PGR | P06401 | 6/20 | 0.75 |
| ▸ | USP2 | O75604 | 5/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.75 |
| ▸ | AR | P10275 | 3/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.75 |
| ▸ | CNR1 | P21554 | 1/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233362 | 0.93 | CYP3A4 (0.76) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL10529305 | 0.90 | CYP3A4 (0.82) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL11232753 | 0.90 | NR3C1 (0.78) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL11223602 | 0.90 | NR3C1 (0.78) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL11226773 | 0.88 | CYP3A4 (0.81) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL24581289 | 0.87 | CYP3A4 (0.85) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354253 | 0.87 | CYP3A4 (0.85) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL11226775 | 0.87 | CYP3A4 (0.80) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL11047296 | 0.87 | CYP3A4 (0.85) | CYP3A4NR3C1PGRUSP2ADORA3 | |
| SCHEMBL11047292 | 0.87 | CYP3A4 (0.85) | CYP3A4NR3C1PGRUSP2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335121-A | TOPICAL ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1982-06-15 | — | — | US | disclosed |