Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11371584 | 0.99 | KMT2A (0.49) | KMT2AMEN1LMNAMAPTNPY1R | |
| SCHEMBL11237174 | 0.93 | KMT2A (0.47) | KMT2AMEN1LMNAMAPTNPY1R | |
| Hydrochloric Acid SCHEMBL11371576 | 0.92 | KMT2A (0.49) | KMT2AMEN1LMNAMAPTNPY1R | |
| Hydrochloric Acid SCHEMBL11370276 | 0.84 | KMT2A (0.36) | KMT2AMEN1LMNAMAPTDRD4 | |
| Hydrochloric Acid SCHEMBL11377709 | 0.82 | KMT2A (0.50) | KMT2AMEN1LMNAMAPTNPY1R | |
| Hydrochloric Acid SCHEMBL11382232 | 0.79 | LMNA (0.46) | KMT2AMEN1LMNAMAPTNPY1R | |
| Hydrochloric Acid SCHEMBL11370273 | 0.78 | KMT2A (0.36) | KMT2AMEN1LMNAMAPTDRD4 | |
| Hydrochloric Acid SCHEMBL11382223 | 0.77 | ADRB2 (0.47) | KMT2AMEN1LMNAMAPTNPY1R | |
| Hydrochloric Acid SCHEMBL11371140 | 0.75 | DRD4 (0.47) | KMT2AMEN1LMNAMAPTNPY1R | |
| SCHEMBL11469923 | 0.74 | DRD4 (0.44) | DRD4ABCB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014928-B1 | PIPERIDINOPROPYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1982-05-05 | — | — | EP | disclosed |
| US-4288442-A | Inhibiting adrenergic β-receptors with piperidinopropyl derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1981-09-08 | — | — | US | disclosed |