Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226987 | 0.85 | KMT2A (0.44) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11276662 | 0.81 | KMT2A (0.45) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11237207 | 0.80 | KMT2A (0.41) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11237203 | 0.77 | EPHX2 (0.43) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11221775 | 0.73 | MAPT (0.53) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11220984 | 0.73 | KMT2A (0.58) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11233929 | 0.72 | MAPT (0.53) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11408691 | 0.69 | MAPT (0.55) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8415420 | 0.68 | MAPT (0.53) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL5660269 | 0.68 | GPR35 (0.53) | KMT2ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348413-A | Anti-arrhythmic N-[3-alkylaminopropyl]-N'-phenylureas | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| WO-1980000151-A1 | N-(3-ALKYLAMINOPROPYL)-N'-PHENYLUREAS | AMERICAN HOME PROD (US) | 1980-02-07 | — | — | WO | disclosed |